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Federal RFI explores how AI can reduce healthcare costs, enhance care

January 7, 2026

The Department of Health and Human Services (HHS) is seeking additional input on how the agency can better adopt and implement artificial intelligence (AI) to advance and improve clinical care. 

The recently issued Request for Information (RFI) further builds on the administration’s AI goals, integrating cutting-edge technologies to drive innovation and improve operations across the entirety of the federal government. The HHS’ efforts represent a “OneHHS” approach to AI implementation as the department works to establish a forward-looking, secure approach to adopting AI tools while preserving patient privacy, civil rights and civil liberties. 

HHS’ core purpose for receiving input for the future of AI integration is to determine how the department can accelerate adoption on a comprehensive scale. In a similar vein to other departments that have already begun integration AI technologies, HHS plans to use these solutions to enhance patient and caregiver experiences and outcomes, reduce provider burden, improve quality of care and reduce healthcare costs. 

Notably, HHS will only leverage tools so far as to not violate HIPAA, prioritizing interoperability and secure patient data. All responses to the RFI will serve to refine and inform the department’s efforts to adopt AI and utilize it in clinical care. The input will guide how the agency will: 

  • Evolve digital health and software regulatory frameworks to account for AI-driven tools while maintaining patient safety. 
  • Simplify and better align reimbursement structures to support the use of efficient, deflationary technologies. 
  • Strengthen implementation science and best practices through research and development (R&D) investments, targeting complex or high-acuity clinical scenarios. 

The department is prioritizing any information that will help define its efforts to optimize regulation, reimbursements and R&D approaches to AI solutions. 

As the department reevaluates its existing regulatory frameworks, it’s seeking additional perspectives on how those frameworks impact AI adoption and use for clinical care. HHS is also interested in determining changes to payment policy to help promote access to high-value AI clinical interventions, foster competition among clinical care AI tool builders and improve access to and affordability of AI tools. Finally, the departments wants additional information on how it may invest in R&D – including public-private partnerships among other methods – to integrate AI in care deliver and create long-term market opportunities. 


Photo by Pixabay

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Adam Rollins

Adam Rollins brings his expertise as a Researcher and Writer to the Managing Editor role for several of SPI's key publications, including Government Contracting Pipeline, Texas Government Insider, and the latest addition, Government Market News. With a rich background as a freelance Content Specialist, Adam has honed a passion for learning and information gathering, delving into various industries. His research and writing have spanned a range of topics, from artificial intelligence (AI) technology, conservation, and project outsourcing, to managed IT services and software development.

Holding a bachelor's degree in English from Texas State University, Adam's proficiency in message development is complemented by his robust research skills and seasoned writing experience. These attributes make him an invaluable asset to SPI, ensuring the delivery of insightful and impactful content to the company's clientele.

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